1VJW

STRUCTURE OF OXIDOREDUCTASE (NADP+(A),FERREDOXIN(A))

1VJW の概要

• エントリーDOI: 10.2210/pdb1vjw/pdb
• 分子名称: FERREDOXIN(A), IRON/SULFUR CLUSTER (3 entities in total)
• 機能のキーワード: thermostable, electron transport, iron-sulfur, 4fe-4s, oxidoreductase
• 由来する生物種: Thermotoga maritima
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 6569.67

構造登録者

Macedo-Ribeiro, S.,Darimont, B.,Sterner, R.,Huber, R. (登録日: 1996-10-09, 公開日: 1996-12-23, 最終更新日: 2024-10-23)

主引用文献

Macedo-Ribeiro, S.,Darimont, B.,Sterner, R.,Huber, R.
Small structural changes account for the high thermostability of 1[4Fe-4S] ferredoxin from the hyperthermophilic bacterium Thermotoga maritima.
Structure, 4:1291-1301, 1996

PubMed Abstract: The characterization of the structural features that account for the high thermostability of some proteins is of great scientific and biotechnological interest. Proteins from hyperthermophilic organisms with optimum growth temperatures of 80 degrees C and higher generally show high intrinsic stabilities. The comparison of high resolution X-ray structures of these proteins with their counterparts from mesophilic organisms has therefore helped to identify potentially stabilizing forces in a number of cases. Small monomeric proteins which comprise only a single domain, such as ferredoxins, are especially suitable for such comparisons since the search for determinants of protein stability is considerably simplified.

PubMed: 8939753
DOI: 10.1016/S0969-2126(96)00137-2

実験手法

X-RAY DIFFRACTION (1.75 Å)