1VBD

POLIOVIRUS (TYPE 1, MAHONEY STRAIN) COMPLEXED WITH R78206

Summary for 1VBD

• Entry DOI: 10.2210/pdb1vbd/pdb
• Descriptor: POLIOVIRUS TYPE 1 MAHONEY, (METHYLPYRIDAZINE PIPERIDINE PROPYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, ... (7 entities in total)
• Functional Keywords: virus coat protein, hydrolase, thiol protease, icosahedral virus, virus
• Biological source: Human poliovirus 1; More
• Cellular location: Capsid protein VP0: Virion. Capsid protein VP4: Virion. Capsid protein VP2: Virion. Capsid protein VP3: Virion. Capsid protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 2C: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3A: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3AB: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Viral protein genome-linked: Virion. Protease 3C: Host cytoplasm. Protein 3CD: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . RNA-directed RNA polymerase: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side : P03300 P03300 P03300
• Total number of polymer chains: 5
• Total formula weight: 98554.19

Authors

Grant, R.A.,Hiremath, C.N.,Filman, D.J.,Syed, R.,Andries, K.,Hogle, J.M. (deposition date: 1996-01-02, release date: 1996-07-11, Last modification date: 2023-04-19)

• Primary citation: Grant, R.A.,Hiremath, C.N.,Filman, D.J.,Syed, R.,Andries, K.,Hogle, J.M.; Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.; Curr.Biol., 4:784-797, 1994; PubMed: 7820548; DOI: 10.1016/S0960-9822(00)00176-7

Experimental method

X-RAY DIFFRACTION (2.9 Å)