1V79
Crystal structures of adenosine deaminase complexed with potent inhibitors
Summary for 1V79
Entry DOI | 10.2210/pdb1v79/pdb |
Related | 1V78 1V7A |
Descriptor | Adenosine deaminase, ZINC ION, 1-{(1R,2S)-1-[2-(2,3,-DICHLOROPHENYL)ETHYL]-2-HYDROXYPROPYL}-1H-IMIDAZOLE-4-CARBOXAMIDE, ... (4 entities in total) |
Functional Keywords | beta barrel, zinc, hydrolase |
Biological source | Bos taurus (cattle) |
Cellular location | Cell membrane; Peripheral membrane protein; Extracellular side (By similarity): P56658 |
Total number of polymer chains | 1 |
Total formula weight | 40749.30 |
Authors | Kinoshita, T. (deposition date: 2003-12-14, release date: 2004-12-21, Last modification date: 2023-12-27) |
Primary citation | Terasaka, T.,Okumura, H.,Tsuji, K.,Kato, T.,Nakanishi, I.,Kinoshita, T.,Kato, Y.,Kuno, M.,Seki, N.,Naoe, Y.,Inoue, T.,Tanaka, K.,Nakamura, K. Structure-based design and synthesis of non-nucleoside, potent, and orally bioavailable adenosine deaminase inhibitors J.Med.Chem., 47:2728-2731, 2004 Cited by PubMed: 15139750DOI: 10.1021/jm0499559 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)