1UVQ
Crystal structure of HLA-DQ0602 in complex with a hypocretin peptide
Summary for 1UVQ
Entry DOI | 10.2210/pdb1uvq/pdb |
Descriptor | HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, OREXIN, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total) |
Functional Keywords | immunology, mhc class ii, diabetes, narcolepsy, autoimmune disease, structural proteomics in europe, spine, structural genomics, immune system |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 3 |
Total formula weight | 49785.54 |
Authors | Siebold, C.,Hansen, B.E.,Wyer, J.R.,Harlos, K.,Esnouf, R.E.,Svejgaard, A.,Bell, J.I.,Strominger, J.L.,Jones, E.Y.,Fugger, L. (deposition date: 2004-01-22, release date: 2004-02-05, Last modification date: 2020-07-29) |
Primary citation | Siebold, C.,Hansen, B.E.,Wyer, J.R.,Harlos, K.,Esnouf, R.E.,Svejgaard, A.,Bell, J.I.,Strominger, J.L.,Jones, E.Y.,Fugger, L. Crystal Structure of Hla-Dq0602 that Protects Against Type 1 Diabetes and Confers Strong Susceptibility to Narcolepsy Proc.Natl.Acad.Sci.USA, 101:1999-, 2004 Cited by PubMed: 14769912DOI: 10.1073/PNAS.0308458100 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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