1UVQ

Crystal structure of HLA-DQ0602 in complex with a hypocretin peptide

1UVQ の概要

• エントリーDOI: 10.2210/pdb1uvq/pdb
• 分子名称: HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, OREXIN, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: immunology, mhc class ii, diabetes, narcolepsy, autoimmune disease, structural proteomics in europe, spine, structural genomics, immune system
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 49785.54

構造登録者

Siebold, C.,Hansen, B.E.,Wyer, J.R.,Harlos, K.,Esnouf, R.E.,Svejgaard, A.,Bell, J.I.,Strominger, J.L.,Jones, E.Y.,Fugger, L. (登録日: 2004-01-22, 公開日: 2004-02-05, 最終更新日: 2020-07-29)

• 主引用文献: Siebold, C.,Hansen, B.E.,Wyer, J.R.,Harlos, K.,Esnouf, R.E.,Svejgaard, A.,Bell, J.I.,Strominger, J.L.,Jones, E.Y.,Fugger, L.; Crystal Structure of Hla-Dq0602 that Protects Against Type 1 Diabetes and Confers Strong Susceptibility to Narcolepsy; Proc.Natl.Acad.Sci.USA, 101:1999-, 2004; PubMed: 14769912; DOI: 10.1073/PNAS.0308458100

実験手法

X-RAY DIFFRACTION (1.8 Å)