1UR8

Interactions of a family 18 chitinase with the designed inhibitor HM508, and its degradation product, chitobiono-delta-lactone

Summary for 1UR8

Entry DOI	10.2210/pdb1ur8/pdb
Related	1E15 1E6N 1E6P 1E6R 1E6Z 1GOI 1GPF 1OGB
Descriptor	CHITINASE B, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-(acetylamido)-2-deoxy-D-glucono-1,5-lactone, GLYCEROL, ... (5 entities in total)
Functional Keywords	hydrolase, chitinase, inhibition, lactone, chitin degradation, glycosidase
Biological source	SERRATIA MARCESCENS
Total number of polymer chains	2
Total formula weight	113382.08
Authors	Vaaje-Kolstad, G.,Vasella, A.,Peter, M.G.,Netter, C.,Houston, D.R.,Westereng, B.,Synstad, B.,Eijsink, V.G.H.,Van Aalten, D.M.F. (deposition date: 2003-10-27, release date: 2004-04-27, Last modification date: 2023-12-13)
Primary citation	Vaaje-Kolstad, G.,Vasella, A.,Peter, M.G.,Netter, C.,Houston, D.R.,Westereng, B.,Synstad, B.,Eijsink, V.G.H.,Van Aalten, D.M.F. Interactions of a Family 18 Chitinase with the Designed Inhibitor Hm508 and its Degradation Product, Chitobiono-Delta-Lactone. J.Biol.Chem., 279:3612-, 2004 Cited by PubMed: 14597613 DOI: 10.1074/JBC.M310057200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation