1UMD

branched-chain 2-oxo acid dehydrogenase (E1) from Thermus thermophilus HB8 with 4-methyl-2-oxopentanoate as an intermediate

1UMD の概要

• エントリーDOI: 10.2210/pdb1umd/pdb
• 関連するPDBエントリー: 1UM9 1UMB 1UMC
• 分子名称: 2-oxo acid dehydrogenase alpha subunit, 2-oxo acid dehydrogenase beta subunit, MAGNESIUM ION, ... (6 entities in total)
• 機能のキーワード: alpha(2)beta(2) tetramer, structural genomics, riken structural genomics/proteomics initiative, rsgi, oxidoreductase
• 由来する生物種: Thermus thermophilus; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 154536.73

構造登録者

Nakai, T.,Nakagawa, N.,Maoka, N.,Masui, R.,Kuramitsu, S.,Kamiya, N.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (登録日: 2003-09-25, 公開日: 2004-03-30, 最終更新日: 2023-10-25)

• 主引用文献: Nakai, T.,Nakagawa, N.,Maoka, N.,Masui, R.,Kuramitsu, S.,Kamiya, N.; Ligand-induced Conformational Changes and a Reaction Intermediate in Branched-chain 2-Oxo Acid Dehydrogenase (E1) from Thermus thermophilus HB8, as Revealed by X-ray Crystallography; J.Mol.Biol., 337:1011-1033, 2004; PubMed: 15033367; DOI: 10.1016/j.jmb.2004.02.011

実験手法

X-RAY DIFFRACTION (1.9 Å)