1UIO

ADENOSINE DEAMINASE (HIS 238 ALA MUTANT)

1UIO の概要

• エントリーDOI: 10.2210/pdb1uio/pdb
• 分子名称: ADENOSINE DEAMINASE, ZINC ION, 6-HYDROXY-7,8-DIHYDRO PURINE NUCLEOSIDE, ... (4 entities in total)
• 機能のキーワード: hydrolase, nucleotide metabolism, zinc cofactor tim barrel
• 由来する生物種: Mus musculus (house mouse)
• 細胞内の位置: Cell membrane; Peripheral membrane protein; Extracellular side (By similarity): P03958
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 39983.77

構造登録者

Wilson, D.K.,Quiocho, F.A. (登録日: 1996-08-30, 公開日: 1997-06-24, 最終更新日: 2024-02-14)

• 主引用文献: Sideraki, V.,Wilson, D.K.,Kurz, L.C.,Quiocho, F.A.,Rudolph, F.B.; Site-directed mutagenesis of histidine 238 in mouse adenosine deaminase: substitution of histidine 238 does not impede hydroxylate formation.; Biochemistry, 35:15019-15028, 1996; PubMed: 8942668; DOI: 10.1021/bi961427e

実験手法

X-RAY DIFFRACTION (2.4 Å)