1UEC

Crystal structure of autoinhibited form of tandem SH3 domain of p47phox

Summary for 1UEC

Entry DOI	10.2210/pdb1uec/pdb
Descriptor	Neutrophil cytosol factor 1 (2 entities in total)
Functional Keywords	nadph oxidase, p47phox, phagocyte, sh3 domain, autoinhibition, signaling protein
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P14598
Total number of polymer chains	1
Total formula weight	22020.73
Authors	Yuzawa, S.,Suzuki, N.N.,Fujioka, Y.,Ogura, K.,Sumimoto, H.,Inagaki, F. (deposition date: 2003-05-11, release date: 2003-05-27, Last modification date: 2023-12-27)
Primary citation	Yuzawa, S.,Suzuki, N.N.,Fujioka, Y.,Ogura, K.,Sumimoto, H.,Inagaki, F. A molecular mechanism for autoinhibition of the tandem SH3 domains of p47phox, the regulatory subunit of the phagocyte NADPH oxidase Genes Cells, 9:443-456, 2004 Cited by PubMed: 15147273 DOI: 10.1111/j.1356-9597.2004.00733.x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.82 Å)

Structure validation