1UC6

Solution Structure of the Carboxyl Terminal Domain of the Ciliary Neurotrophic Factor Receptor

1UC6 の概要

• エントリーDOI: 10.2210/pdb1uc6/pdb
• 分子名称: Ciliary Neurotrophic Factor Receptor alpha (1 entity in total)
• 機能のキーワード: cytokine, ciliary neurotrophic factor, leukemia inhibitory factor, cytokine receptor, fibronectin type iii domain-like topology, seven beta-strands, two anti-parallel beta-sheets, protein binding
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cell membrane; Lipid-anchor, GPI-anchor: P26992
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 12333.68

構造登録者

Man, D.,He, W.,Sze, K.H.,Ke, G.,Smith, D.K.,Ip, N.Y.,Zhu, G. (登録日: 2003-04-08, 公開日: 2004-08-10, 最終更新日: 2023-12-27)

• 主引用文献: Man, D.,He, W.,Sze, K.H.,Gong, K.,Smith, D.K.,Zhu, G.,Ip, N.Y.; Solution structure of the C-terminal domain of the ciliary neurotrophic factor (CNTF) receptor and ligand free associations among components of the CNTF receptor complex; J.Biol.Chem., 278:23285-23294, 2003; PubMed: 12707266; DOI: 10.1074/jbc.M301976200

実験手法

SOLUTION NMR