1UBF

MsREcA-ATPgS complex

1UBF の概要

• エントリーDOI: 10.2210/pdb1ubf/pdb
• 関連するPDBエントリー: 1g19 1mo3 1UBC 1UBE 1UBG
• 分子名称: RecA, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER (3 entities in total)
• 機能のキーワード: recombination, dna-repair
• 由来する生物種: Mycobacterium smegmatis
• 細胞内の位置: Cytoplasm (By similarity): Q59560
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 37867.74

構造登録者

Datta, S.,Krishna, R.,Ganesh, N.,Chandra, N.R.,Muniyappa, K.,Vijayan, M. (登録日: 2003-04-04, 公開日: 2003-07-22, 最終更新日: 2023-10-25)

主引用文献

Datta, S.,Krishna, R.,Ganesh, N.,Chandra, N.R.,Muniyappa, K.,Vijayan, M.
Crystal Structures of Mycobacterium smegmatis RecA and Its Nucleotide Complexes
J.BACTERIOL., 185:4280-4284, 2003

PubMed Abstract: The crystal structures of Mycobacterium smegmatis RecA (RecA(Ms)) and its complexes with ADP, ATPgammaS, and dATP show that RecA(Ms) has an expanded binding site like that in Mycobacterium tuberculosis RecA, although there are small differences between the proteins in their modes of nucleotide binding. Nucleotide binding is invariably accompanied by the movement of Gln 196, which appears to provide the trigger for transmitting the effect of nucleotide binding to the DNA-binding loops. These observations provide a framework for exploring the known properties of the RecA proteins.

PubMed: 12837805
DOI: 10.1128/JB.185.14.4280-4284.2003

実験手法

X-RAY DIFFRACTION (3.5 Å)