1U21
transthyretin with tethered inhibitor on one monomer.
Summary for 1U21
Entry DOI | 10.2210/pdb1u21/pdb |
Descriptor | Transthyretin, 2-[(3,5-DICHLORO-4-TRIOXIDANYLPHENYL)AMINO]BENZOIC ACID (3 entities in total) |
Functional Keywords | transthyretin, amyloid, hormone-growth factor complex, hormone/growth factor |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P02766 |
Total number of polymer chains | 2 |
Total formula weight | 28214.96 |
Authors | Wiseman, R.L.,Johnson, S.M.,Kelker, M.S.,Foss, T.,Wilson, I.A.,Kelly, J.W. (deposition date: 2004-07-16, release date: 2005-06-28, Last modification date: 2023-08-23) |
Primary citation | Wiseman, R.L.,Johnson, S.M.,Kelker, M.S.,Foss, T.,Wilson, I.A.,Kelly, J.W. Kinetic stabilization of an oligomeric protein by a single ligand binding event J.Am.Chem.Soc., 127:5540-5551, 2005 Cited by PubMed: 15826192DOI: 10.1021/ja042929f PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.69 Å) |
Structure validation
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