1TZH

Crystal Structure of the Fab YADS1 Complexed with h-VEGF

Summary for 1TZH

• Entry DOI: 10.2210/pdb1tzh/pdb
• Related: 1tzi
• Descriptor: Vascular endothelial growth factor A, Fab YADS1 Light Chain, Fab YADS1 Heavy Chain, ... (4 entities in total)
• Functional Keywords: phage display, antibody library, protein engineering, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P15692
• Total number of polymer chains: 6
• Total formula weight: 118570.13

Authors

Fellouse, F.A.,Wiesmann, C.,Sidhu, S.S. (deposition date: 2004-07-09, release date: 2004-08-31, Last modification date: 2023-08-23)

• Primary citation: Fellouse, F.A.,Wiesmann, C.,Sidhu, S.S.; Synthetic antibodies from a four-amino-acid code: A dominant role for tyrosine in antigen recognition; Proc.Natl.Acad.Sci.USA, 101:12467-12472, 2004; PubMed: 15306681; DOI: 10.1073/pnas.0401786101

Experimental method

X-RAY DIFFRACTION (2.6 Å)