1TYN

ATOMIC STRUCTURE OF THE TRYPSIN-CYCLOTHEONAMIDE A COMPLEX: LESSONS FOR THE DESIGN OF SERINE PROTEASE INHIBITORS

Summary for 1TYN

• Entry DOI: 10.2210/pdb1tyn/pdb
• Descriptor: BETA-TRYPSIN, CYCLOTHEONAMIDE A (3 entities in total)
• Functional Keywords: hydrolase(serine protease)
• Biological source: Bos taurus (cattle)
• Cellular location: Secreted, extracellular space: P00760
• Total number of polymer chains: 1
• Total formula weight: 24056.08

Authors

Lee, A.Y.,Hagihara, M.,Karmacharya, R.,Albers, M.W.,Schreiber, S.L.,Clardy, J. (deposition date: 1994-09-19, release date: 1995-01-26, Last modification date: 2011-07-13)

• Primary citation: Lee, A.Y.,Hagihara, M.,Karmacharya, R.,Albers, M.W.,Schreiber, S.L.,Clardy, J.; Atomic Structure of the Trypsin-Cyclotheonamide a Complex: Lessons for the Design of Serine Protease Inhibitors; J.Am.Chem.Soc., 115:12619-, 1993

Experimental method

X-RAY DIFFRACTION (2 Å)