1TSI
STRUCTURE OF THE COMPLEX BETWEEN TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE AND N-HYDROXY-4-PHOSPHONO-BUTANAMIDE: BINDING AT THE ACTIVE SITE DESPITE AN "OPEN" FLEXIBLE LOOP
Summary for 1TSI
Entry DOI | 10.2210/pdb1tsi/pdb |
Descriptor | TRIOSEPHOSPHATE ISOMERASE, N-HYDROXY-4-PHOSPHONO-BUTANAMIDE (3 entities in total) |
Functional Keywords | isomerase(intramolecular oxidoreductase) |
Biological source | Trypanosoma brucei brucei |
Cellular location | Glycosome: P04789 |
Total number of polymer chains | 2 |
Total formula weight | 54084.98 |
Authors | Verlinde, C.L.M.J. (deposition date: 1992-11-19, release date: 1994-01-31, Last modification date: 2024-02-14) |
Primary citation | Verlinde, C.L.,Witmans, C.J.,Pijning, T.,Kalk, K.H.,Hol, W.G.,Callens, M.,Opperdoes, F.R. Structure of the complex between trypanosomal triosephosphate isomerase and N-hydroxy-4-phosphono-butanamide: binding at the active site despite an "open" flexible loop conformation. Protein Sci., 1:1578-1584, 1992 Cited by PubMed: 1304889PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.84 Å) |
Structure validation
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