1TRG
E. COLI THYMIDYLATE SYNTHASE IN SYMMETRIC COMPLEX WITH CB3717 AND 2'-DEOXYURIDINE 5'-MONOPHOSPHATE (DUMP)
Summary for 1TRG
Entry DOI | 10.2210/pdb1trg/pdb |
Descriptor | THYMIDYLATE SYNTHASE, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, ... (4 entities in total) |
Functional Keywords | methyltransferase, symmetric ternary complex |
Biological source | Escherichia coli |
Cellular location | Cytoplasm: P0A884 |
Total number of polymer chains | 1 |
Total formula weight | 31329.31 |
Authors | Stout, T.J.,Sage, C.R.,Stroud, R.M. (deposition date: 1998-05-21, release date: 1998-08-12, Last modification date: 2023-08-09) |
Primary citation | Stout, T.J.,Sage, C.R.,Stroud, R.M. The additivity of substrate fragments in enzyme-ligand binding. Structure, 6:839-848, 1998 Cited by PubMed: 9687366DOI: 10.1016/S0969-2126(98)00086-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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