1TRG

E. COLI THYMIDYLATE SYNTHASE IN SYMMETRIC COMPLEX WITH CB3717 AND 2'-DEOXYURIDINE 5'-MONOPHOSPHATE (DUMP)

Summary for 1TRG

Entry DOI	10.2210/pdb1trg/pdb
Descriptor	THYMIDYLATE SYNTHASE, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, ... (4 entities in total)
Functional Keywords	methyltransferase, symmetric ternary complex
Biological source	Escherichia coli
Cellular location	Cytoplasm: P0A884
Total number of polymer chains	1
Total formula weight	31329.31
Authors	Stout, T.J.,Sage, C.R.,Stroud, R.M. (deposition date: 1998-05-21, release date: 1998-08-12, Last modification date: 2023-08-09)
Primary citation	Stout, T.J.,Sage, C.R.,Stroud, R.M. The additivity of substrate fragments in enzyme-ligand binding. Structure, 6:839-848, 1998 Cited by PubMed: 9687366 DOI: 10.1016/S0969-2126(98)00086-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation