1TQN
Crystal Structure of Human Microsomal P450 3A4
Summary for 1TQN
| Entry DOI | 10.2210/pdb1tqn/pdb |
| Related | 1PQ2 |
| Descriptor | cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE (3 entities in total) |
| Functional Keywords | p450, cyp3a4, monooxygenase, drug metabolizing enzyme, oxidoreductase, heme |
| Biological source | Homo sapiens (human) |
| Cellular location | Endoplasmic reticulum membrane; Single-pass membrane protein: P08684 |
| Total number of polymer chains | 1 |
| Total formula weight | 56211.12 |
| Authors | Yano, J.K.,Wester, M.R.,Schoch, G.A.,Griffin, K.J.,Stout, C.D.,Johnson, E.F. (deposition date: 2004-06-17, release date: 2004-07-27, Last modification date: 2024-02-14) |
| Primary citation | Yano, J.K.,Wester, M.R.,Schoch, G.A.,Griffin, K.J.,Stout, C.D.,Johnson, E.F. The Structure of Human Microsomal Cytochrome P450 3A4 Determined by X-ray Crystallography to 2.05-A Resolution J.Biol.Chem., 279:38091-38094, 2004 Cited by PubMed: 15258162DOI: 10.1074/jbc.C400293200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
Download full validation report
