1TNF
THE STRUCTURE OF TUMOR NECROSIS FACTOR-ALPHA AT 2.6 ANGSTROMS RESOLUTION. IMPLICATIONS FOR RECEPTOR BINDING
Summary for 1TNF
Entry DOI | 10.2210/pdb1tnf/pdb |
Descriptor | TUMOR NECROSIS FACTOR-ALPHA (1 entity in total) |
Functional Keywords | lymphokine |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane; Single-pass type II membrane protein. Tumor necrosis factor, soluble form: Secreted: P01375 |
Total number of polymer chains | 3 |
Total formula weight | 52106.19 |
Authors | Eck, M.J.,Sprang, S.R. (deposition date: 1989-08-25, release date: 1990-01-15, Last modification date: 2024-06-05) |
Primary citation | Eck, M.J.,Sprang, S.R. The structure of tumor necrosis factor-alpha at 2.6 A resolution. Implications for receptor binding. J.Biol.Chem., 264:17595-17605, 1989 Cited by PubMed: 2551905PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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