1TMN

Binding of n-carboxymethyl dipeptide inhibitors to thermolysin determined by x-ray crystallography. a novel class of transition-state analogues for zinc peptidases

1TMN の概要

• エントリーDOI: 10.2210/pdb1tmn/pdb
• 関連するBIRD辞書のPRD_ID: PRD_000380
• 分子名称: THERMOLYSIN, N-[(1R)-1-carboxy-3-phenylpropyl]-L-leucyl-L-tryptophan, CALCIUM ION, ... (5 entities in total)
• 機能のキーワード: metalloproteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Bacillus thermoproteolyticus
• 細胞内の位置: Secreted: P00800
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 35067.59

構造登録者

Monzingo, A.F.,Matthews, B.W. (登録日: 1987-06-29, 公開日: 1989-01-09, 最終更新日: 2022-11-23)

• 主引用文献: Monzingo, A.F.,Matthews, B.W.; Binding of N-carboxymethyl dipeptide inhibitors to thermolysin determined by X-ray crystallography: a novel class of transition-state analogues for zinc peptidases; Biochemistry, 23:5724-5729, 1984; PubMed: 6395881; DOI: 10.1021/bi00319a010

実験手法

X-RAY DIFFRACTION (1.9 Å)