1TLP
CRYSTALLOGRAPHIC STRUCTURAL ANALYSIS OF PHOSPHORAMIDATES AS INHIBITORS AND TRANSITION-STATE ANALOGS OF THERMOLYSIN
Summary for 1TLP
Entry DOI | 10.2210/pdb1tlp/pdb |
Related PRD ID | PRD_000638 |
Descriptor | THERMOLYSIN, N-ALPHA-L-RHAMNOPYRANOSYLOXY(HYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | metalloproteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Bacillus thermoproteolyticus |
Cellular location | Secreted: P00800 |
Total number of polymer chains | 1 |
Total formula weight | 35131.53 |
Authors | Tronrud, D.E.,Monzingo, A.F.,Matthews, B.W. (deposition date: 1987-06-29, release date: 1989-01-09, Last modification date: 2024-03-13) |
Primary citation | Tronrud, D.E.,Monzingo, A.F.,Matthews, B.W. Crystallographic structural analysis of phosphoramidates as inhibitors and transition-state analogs of thermolysin. Eur.J.Biochem., 157:261-268, 1986 Cited by PubMed: 3709536DOI: 10.1111/j.1432-1033.1986.tb09664.x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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