1THS

STRUCTURES OF THROMBIN COMPLEXES WITH A DESIGNED AND A NATURAL EXOSITE INHIBITOR

1THS の概要

• エントリーDOI: 10.2210/pdb1ths/pdb
• 分子名称: ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), SYNTHETIC INHIBITOR, ... (4 entities in total)
• 機能のキーワード: serine proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted, extracellular space: P00734 P00734
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 35206.16

構造登録者

Qiu, X.,Yin, M.,Padmanabhan, K.P.,Krstenansky, J.L.,Tulinsky, A. (登録日: 1993-06-16, 公開日: 1994-01-31, 最終更新日: 2011-07-13)

• 主引用文献: Qiu, X.,Yin, M.,Padmanabhan, K.P.,Krstenansky, J.L.,Tulinsky, A.; Structures of thrombin complexes with a designed and a natural exosite peptide inhibitor.; J.Biol.Chem., 268:20318-20326, 1993; PubMed: 8376390

実験手法

X-RAY DIFFRACTION (2.2 Å)