1THL

Thermolysin complexed with a novel glutaramide derivative, n-(1-(2(r,s)-carboxy-4-phenylbutyl) cyclopentylcarbonyl)-(s)-tryptophan

Summary for 1THL

Entry DOI	10.2210/pdb1thl/pdb
Related PRD ID	PRD_000237
Descriptor	THERMOLYSIN, CALCIUM ION, ZINC ION, ... (5 entities in total)
Functional Keywords	metalloproteinase, glutaramide derivative, thermolysin, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Bacillus thermoproteolyticus
Cellular location	Secreted: P00800
Total number of polymer chains	1
Total formula weight	35064.59
Authors	Holland, D.R.,Matthews, B.W. (deposition date: 1993-11-17, release date: 1994-01-31, Last modification date: 2023-08-09)
Primary citation	Holland, D.R.,Barclay, P.L.,Danilewicz, J.C.,Matthews, B.W.,James, K. Inhibition of Thermolysin and Neutral Endopeptidase 24.11 By a Novel Glutaramide Derivative; X-Ray Structure Determination of the Thermolysin-Inhibitor Complex Biochemistry, 33:51-56, 1994 Cited by PubMed: 8286362 DOI: 10.1021/bi00167a007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation