1TFZ

Structural basis for herbicidal inhibitor selectivity revealed by comparison of crystal structures of plant and mammalian 4-hydroxyphenylpyruvate dioxygenases

Summary for 1TFZ

Entry DOI	10.2210/pdb1tfz/pdb
Related	1SQD 1SQI
Descriptor	4-hydroxyphenylpyruvate dioxygenase, FE (III) ION, (1-TERT-BUTYL-5-HYDROXY-1H-PYRAZOL-4-YL)[6-(METHYLSULFONYL)-4'-METHOXY-2-METHYL-1,1'-BIPHENYL-3-YL]METHANONE, ... (4 entities in total)
Functional Keywords	arabidopsis thaliana, 4-hydroxyphenylpyruvate dioxygenase, hppd, athppd, oxidoreductase
Biological source	Arabidopsis thaliana (thale cress)
Cellular location	Cytoplasm : P93836
Total number of polymer chains	1
Total formula weight	47282.17
Authors	Yang, C.,Pflugrath, J.W.,Camper, D.L.,Foster, M.L.,Pernich, D.J.,Walsh, T.A. (deposition date: 2004-05-27, release date: 2004-08-17, Last modification date: 2023-08-23)
Primary citation	Yang, C.,Pflugrath, J.W.,Camper, D.L.,Foster, M.L.,Pernich, D.J.,Walsh, T.A. Structural basis for herbicidal inhibitor selectivity revealed by comparison of crystal structures of plant and Mammalian 4-hydroxyphenylpyruvate dioxygenases Biochemistry, 43:10414-10423, 2004 Cited by PubMed: 15301540 DOI: 10.1021/bi049323o PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation