1TDW
Crystal structure of double truncated human phenylalanine hydroxylase BH4-responsive PKU mutant A313T.
Summary for 1TDW
Entry DOI | 10.2210/pdb1tdw/pdb |
Related | 1PAH |
Descriptor | Phenylalanine-4-hydroxylase, FE (III) ION (3 entities in total) |
Functional Keywords | phenylalanine catabolism, oxidoreductase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 35786.39 |
Authors | Erlandsen, H.,Pey, A.L.,Gamez, A.,Perez, B.,Desviat, L.R.,Aguado, C.,Koch, R.,Surendran, S.,Tyring, S.,Matalon, R.,Scriver, C.R.,Ugarte, M.,Martinez, A.,Stevens, R.C. (deposition date: 2004-05-24, release date: 2004-11-30, Last modification date: 2023-08-23) |
Primary citation | Erlandsen, H.,Pey, A.L.,Gamez, A.,Perez, B.,Desviat, L.R.,Aguado, C.,Koch, R.,Surendran, S.,Tyring, S.,Matalon, R.,Scriver, C.R.,Ugarte, M.,Martinez, A.,Stevens, R.C. Correction of kinetic and stability defects by tetrahydrobiopterin in phenylketonuria patients with certain phenylalanine hydroxylase mutations. Proc.Natl.Acad.Sci.Usa, 101:16903-16908, 2004 Cited by PubMed: 15557004DOI: 10.1073/pnas.0407256101 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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