1TCW

SIV PROTEASE COMPLEXED WITH INHIBITOR SB203386

1TCW の概要

• エントリーDOI: 10.2210/pdb1tcw/pdb
• 分子名称: SIV PROTEASE, (2R,4S,5S,1'S)-2-PHENYLMETHYL-4-HYDROXY-5-(TERT-BUTOXYCARBONYL)AMINO-6-PHENYL HEXANOYL-N-(1'-IMIDAZO-2-YL)-2'-METHYLPROPANAMIDE (3 entities in total)
• 機能のキーワード: aids, polyprotein, hydrolase, aspartyl protease, endonuclease, rna-directed dna polymerase, acid protease, hydrolase (acid protease)
• 由来する生物種: Simian immunodeficiency virus
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 22520.28

構造登録者

Hoog, S.S.,Abdel-Meguid, S.S. (登録日: 1996-06-05, 公開日: 1996-12-07, 最終更新日: 2024-02-14)

• 主引用文献: Hoog, S.S.,Towler, E.M.,Zhao, B.,Doyle, M.L.,Debouck, C.,Abdel-Meguid, S.S.; Human immunodeficiency virus protease ligand specificity conferred by residues outside of the active site cavity.; Biochemistry, 35:10279-10286, 1996; PubMed: 8756683; DOI: 10.1021/bi960179j

実験手法

X-RAY DIFFRACTION (2.4 Å)