1TCV

Crystal Structure of the Purine Nucleoside Phosphorylase from Schistosoma mansoni in complex with Non-detergent Sulfobetaine 195 and acetate

Summary for 1TCV

Entry DOI	10.2210/pdb1tcv/pdb
Related	1TCU 1TD1
Descriptor	purine-nucleoside phosphorylase, ACETATE ION, ETHYL DIMETHYL AMMONIO PROPANE SULFONATE, ... (4 entities in total)
Functional Keywords	purine nucleoside phosphorylase, transferase
Biological source	Schistosoma mansoni
Total number of polymer chains	3
Total formula weight	94354.73
Authors	Pereira, H.D.,Franco, G.R.,Cleasby, A.,Garratt, R.C. (deposition date: 2004-05-21, release date: 2005-05-24, Last modification date: 2024-04-03)
Primary citation	Pereira, H.D.,Franco, G.R.,Cleasby, A.,Garratt, R.C. Structures for the Potential Drug Target Purine Nucleoside Phosphorylase from Schistosoma mansoni Causal Agent of Schistosomiasis. J.Mol.Biol., 353:584-599, 2005 Cited by PubMed: 16182308 DOI: 10.1016/j.jmb.2005.08.045 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation