1TCE

SOLUTION NMR STRUCTURE OF THE SHC SH2 DOMAIN COMPLEXED WITH A TYROSINE-PHOSPHORYLATED PEPTIDE FROM THE T-CELL RECEPTOR, MINIMIZED AVERAGE STRUCTURE

1TCE の概要

• エントリーDOI: 10.2210/pdb1tce/pdb
• 分子名称: SHC, PHOSPHOPEPTIDE OF THE ZETA CHAIN OF T CELL RECEPTOR (2 entities in total)
• 機能のキーワード: sh2 domain, complex (signal transduction-peptide), complex (signal transduction-peptide) complex, complex (signal transduction/peptide)
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm. Isoform p46Shc: Mitochondrion matrix. Isoform p66Shc: Mitochondrion (By similarity): P29353; Membrane; Single-pass type I membrane protein: P20963
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 13653.22

構造登録者

Zhou, M.-M.,Meadows, R.P.,Logan, T.M.,Yoon, H.S.,Wade, W.R.,Ravichandran, K.S.,Burakoff, S.J.,Feisk, S.W. (登録日: 1996-03-27, 公開日: 1997-05-15, 最終更新日: 2022-03-02)

• 主引用文献: Zhou, M.M.,Meadows, R.P.,Logan, T.M.,Yoon, H.S.,Wade, W.S.,Ravichandran, K.S.,Burakoff, S.J.,Fesik, S.W.; Solution structure of the Shc SH2 domain complexed with a tyrosine-phosphorylated peptide from the T-cell receptor.; Proc.Natl.Acad.Sci.USA, 92:7784-7788, 1995; PubMed: 7544002; DOI: 10.1073/pnas.92.17.7784

実験手法

SOLUTION NMR