1T44
Structural basis of actin sequestration by thymosin-B4: Implications for arp2/3 activation
Summary for 1T44
Entry DOI | 10.2210/pdb1t44/pdb |
Related | 1P8Z |
Descriptor | Chimera of Gelsolin domain 1 and C-Terminal domain of thymosin Beta-4, Actin, alpha, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | structural protein |
Biological source | Homo sapiens (human, house mouse) More |
Cellular location | Cytoplasm, cytoskeleton: P20065 |
Total number of polymer chains | 2 |
Total formula weight | 58533.06 |
Authors | Irobi, E.,Aguda, A.H.,Larsson, M.,Burtnick, L.D.,Robinson, R.C. (deposition date: 2004-04-28, release date: 2004-09-07, Last modification date: 2023-08-23) |
Primary citation | Irobi, E.,Aguda, A.H.,Larsson, M.,Guerin, C.,Yin, H.L.,Burtnick, L.D.,Blanchoin, L.,Robinson, R.C. Structural basis of actin sequestration by thymosin-beta4: implications for WH2 proteins. Embo J., 23:3599-3608, 2004 Cited by PubMed: 15329672DOI: 10.1038/sj.emboj.7600372 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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