1T0P

Structural Basis of ICAM recognition by integrin alpahLbeta2 revealed in the complex structure of binding domains of ICAM-3 and alphaLbeta2 at 1.65 A

1T0P の概要

• エントリーDOI: 10.2210/pdb1t0p/pdb
• 分子名称: Integrin alpha-L, Intercellular adhesion molecule-3, MAGNESIUM ION, ... (5 entities in total)
• 機能のキーワード: rossmann fold; ig-super family domain, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 29403.53

構造登録者

Song, G.,Yang, Y.T.,Liu, J.H.,Shimaoko, M.,Springer, T.A.,Wang, J.H. (登録日: 2004-04-12, 公開日: 2005-03-08, 最終更新日: 2021-10-27)

• 主引用文献: Song, G.,Yang, Y.,Liu, J.H.,Casasnovas, J.M.,Shimaoka, M.,Springer, T.A.,Wang, J.H.; An atomic resolution view of ICAM recognition in a complex between the binding domains of ICAM-3 and integrin alphaLbeta2.; Proc.Natl.Acad.Sci.Usa, 102:3366-3371, 2005; PubMed: 15728350; DOI: 10.1073/pnas.0500200102

実験手法

X-RAY DIFFRACTION (1.66 Å)