1SZO

Crystal Structure Analysis of the 6-Oxo Camphor Hydrolase His122Ala Mutant Bound to Its Natural Product (2S,4S)-alpha-Campholinic Acid

1SZO の概要

• エントリーDOI: 10.2210/pdb1szo/pdb
• 関連するPDBエントリー: 1DUB 1O8U
• 分子名称: 6-oxocamphor hydrolase, (2S,4S)-4-(2,2-DIHYDROXYETHYL)-2,3,3-TRIMETHYLCYCLOPENTANONE, CALCIUM ION, ... (4 entities in total)
• 機能のキーワード: enzyme-product complex, hydrolase
• 由来する生物種: Rhodococcus sp. NCIMB 9784
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 343749.35

構造登録者

Leonard, P.M.,Grogan, G. (登録日: 2004-04-06, 公開日: 2004-06-29, 最終更新日: 2023-08-23)

• 主引用文献: Leonard, P.M.,Grogan, G.; Structure of 6-oxo camphor hydrolase H122A mutant bound to its natural product, (2S,4S)-alpha-campholinic acid: mutant structure suggests an atypical mode of transition state binding for a crotonase homolog.; J.Biol.Chem., 279:31312-31317, 2004; PubMed: 15138275; DOI: 10.1074/jbc.M403514200

実験手法

X-RAY DIFFRACTION (1.9 Å)