1STC

CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT IN COMPLEX WITH STAUROSPORINE

1STC の概要

• エントリーDOI: 10.2210/pdb1stc/pdb
• 分子名称: CAMP-DEPENDENT PROTEIN KINASE, PROTEIN KINASE INHIBITOR, STAUROSPORINE, ... (4 entities in total)
• 機能のキーワード: protein kinase, staurosporine, camp, phosphorylation, complex (transferase-inhibitor), serine/threonine-protein kinase, complex (transferase-inhibitor) complex, complex (transferase/inhibitor)
• 由来する生物種: Bos taurus (cattle)
• 細胞内の位置: Cytoplasm: P00517
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 43479.34

構造登録者

Prade, L.,Engh, R.A.,Girod, A.,Kinzel, V.,Huber, R.,Bossemeyer, D. (登録日: 1997-10-10, 公開日: 1998-02-25, 最終更新日: 2023-08-09)

• 主引用文献: Prade, L.,Engh, R.A.,Girod, A.,Kinzel, V.,Huber, R.,Bossemeyer, D.; Staurosporine-induced conformational changes of cAMP-dependent protein kinase catalytic subunit explain inhibitory potential.; Structure, 5:1627-1637, 1997; PubMed: 9438863; DOI: 10.1016/S0969-2126(97)00310-9

実験手法

X-RAY DIFFRACTION (2.3 Å)