1SR7
Progesterone Receptor Hormone Binding Domain with Bound Mometasone Furoate
Summary for 1SR7
Entry DOI | 10.2210/pdb1sr7/pdb |
Related | 1A28 1E3K 1SQN |
Descriptor | Progesterone receptor, MOMETASONE FUROATE, SULFATE ION, ... (5 entities in total) |
Functional Keywords | progesterone receptor, mometasone, progesterone, nuclear receptor, hormone receptor, transcription |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus. Isoform A: Nucleus: P06401 |
Total number of polymer chains | 2 |
Total formula weight | 60822.76 |
Authors | Madauss, K.P.,Deng, S.-J.,Austin, R.J.,Lambert, M.H.,McLay, I.,Pritchard, J.,Short, S.A.,Stewart, E.L.,Uings, I.J.,Williams, S.P. (deposition date: 2004-03-22, release date: 2004-06-22, Last modification date: 2023-08-23) |
Primary citation | Madauss, K.P.,Deng, S.-J.,Austin, R.J.,Lambert, M.H.,McLay, I.,Pritchard, J.,Short, S.A.,Stewart, E.L.,Uings, I.J.,Williams, S.P. Progesterone receptor ligand binding pocket flexibility: crystal structures of the norethindrone and mometasone furoate complexes J.Med.Chem., 47:3381-3387, 2004 Cited by PubMed: 15189034DOI: 10.1021/jm030640n PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.46 Å) |
Structure validation
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