1SL5

Crystal Structure of DC-SIGN carbohydrate recognition domain complexed with LNFP III (Dextra L504).

Summary for 1SL5

DescriptormDC-SIGN1B type I isoform, BETA-D-GALACTOSE, N-ACETYL-D-GLUCOSAMINE, ... (7 entities in total)
Functional Keywordsdc-sign, c-type lectin, sugar binding protein
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total molecular weight16980.93
Authors
Guo, Y.,Feinberg, H.,Conroy, E.,Mitchell, D.A.,Alvarez, R.,Blixt, O.,Taylor, M.E.,Weis, W.I.,Drickamer, K. (deposition date: 2004-03-05, release date: 2004-06-15, Last modification date: 2011-07-13)
Primary citation
Guo, Y.,Feinberg, H.,Conroy, E.,Mitchell, D.A.,Alvarez, R.,Blixt, O.,Taylor, M.E.,Weis, W.I.,Drickamer, K.
Structural basis for distinct ligand-binding and targeting properties of the receptors DC-SIGN and DC-SIGNR
Nat.Struct.Mol.Biol., 11:591-598, 2004
PubMed: 15195147 (PDB entries with the same primary citation)
DOI: 10.1038/nsmb784
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.8 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.21470.8%1.7%1.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution