1SE6

Crystal Structure of Streptomyces Coelicolor A3(2) CYP158A2 from antibiotic biosynthetic pathways

Summary for 1SE6

• Entry DOI: 10.2210/pdb1se6/pdb
• Related: 1S1F
• Descriptor: putative cytochrome P450, SPERMINE (FULLY PROTONATED FORM), PROTOPORPHYRIN IX CONTAINING FE, ... (5 entities in total)
• Functional Keywords: streptomyces, cytochrome p450 oxidoreductase, cyp158a2, antibiotic biosynthesis, oxidoreductase
• Biological source: Streptomyces coelicolor
• Total number of polymer chains: 2
• Total formula weight: 91004.15

Authors

Zhao, B.,Lamb, D.C.,Lei, L.,Sundaramoorthy, M.,Podust, L.M.,Waterman, M.R. (deposition date: 2004-02-16, release date: 2005-01-25, Last modification date: 2023-08-23)

• Primary citation: Zhao, B.,Guengerich, F.P.,Bellamine, A.,Lamb, D.C.,Izumikawa, M.,Lei, L.,Podust, L.M.,Sundaramoorthy, M.,Kalaitzis, J.A.,Reddy, L.M.,Kelly, S.L.,Moore, B.S.,Stec, D.,Voehler, M.,Falck, J.R.,Shimada, T.,Waterman, M.R.; Binding of Two Flaviolin Substrate Molecules, Oxidative Coupling, and Crystal Structure of Streptomyces coelicolor A3(2) Cytochrome P450 158A2.; J.Biol.Chem., 280:11599-11607, 2005; PubMed: 15659395; DOI: 10.1074/jbc.M410933200

Experimental method

X-RAY DIFFRACTION (1.75 Å)