1SE3

STAPHYLOCOCCAL ENTEROTOXIN B COMPLEXED WITH GM3 TRISACCHARIDE

1SE3 の概要

• エントリーDOI: 10.2210/pdb1se3/pdb
• 分子名称: STAPHYLOCOCCAL ENTEROTOXIN B, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: toxin, superantigen, seb, sialyllactose, complex, enterotoxin
• 由来する生物種: Staphylococcus aureus
• 細胞内の位置: Secreted: P01552
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29044.62

構造登録者

Swaminathan, S.,Sax, M. (登録日: 1996-10-11, 公開日: 1997-06-16, 最終更新日: 2024-10-30)

主引用文献

Swaminathan, S.,Furey, W.,Pletcher, J.,Sax, M.
Residues defining V beta specificity in staphylococcal enterotoxins.
Nat.Struct.Biol., 2:680-686, 1995

PubMed Abstract: The three-dimensional structure of staphylococcal enterotoxin C2 has been determined at 2.7 A resolution by x-ray diffraction, while the structures of enterotoxins A and E have been modelled based on their sequence homology to other staphylococcal enterotoxins. The T-cell receptor-binding sites of staphylococcal enterotoxin (SE) B and SEC2 are compared and the stereochemical interactions likely to be responsible for their differing V beta specificities are identified. A similar comparison is made between SEA and SEE.

PubMed: 7552730
DOI: 10.1038/nsb0895-680

実験手法

X-RAY DIFFRACTION (2.3 Å)