1SCF

HUMAN RECOMBINANT STEM CELL FACTOR

Summary for 1SCF

Entry DOI	10.2210/pdb1scf/pdb
Descriptor	STEM CELL FACTOR, PENTAETHYLENE GLYCOL, CALCIUM ION, ... (4 entities in total)
Functional Keywords	human stem cell factor, steel factor, kit ligand, mast cell growth factor, hormone-growth factor complex, hormone/growth factor
Biological source	Homo sapiens (human)
Cellular location	Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Cell membrane; Single-pass type I membrane protein (By similarity). Soluble KIT ligand: Secreted: P21583
Total number of polymer chains	4
Total formula weight	124655.41
Authors	Jiang, X.,Gurel, O.,Langley, K.E.,Hendrickson, W.A. (deposition date: 1998-06-04, release date: 2000-07-07, Last modification date: 2022-12-21)
Primary citation	Jiang, X.,Gurel, O.,Mendiaz, E.A.,Stearns, G.W.,Clogston, C.L.,Lu, H.S.,Osslund, T.D.,Syed, R.S.,Langley, K.E.,Hendrickson, W.A. Structure of the active core of human stem cell factor and analysis of binding to its receptor kit. EMBO J., 19:3192-3203, 2000 Cited by PubMed: 10880433 DOI: 10.1093/emboj/19.13.3192 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation