1SCF

HUMAN RECOMBINANT STEM CELL FACTOR

1SCF の概要

• エントリーDOI: 10.2210/pdb1scf/pdb
• 分子名称: STEM CELL FACTOR, PENTAETHYLENE GLYCOL, CALCIUM ION, ... (4 entities in total)
• 機能のキーワード: human stem cell factor, steel factor, kit ligand, mast cell growth factor, hormone-growth factor complex, hormone/growth factor
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Cell membrane; Single-pass type I membrane protein (By similarity). Soluble KIT ligand: Secreted: P21583
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 124655.41

構造登録者

Jiang, X.,Gurel, O.,Langley, K.E.,Hendrickson, W.A. (登録日: 1998-06-04, 公開日: 2000-07-07, 最終更新日: 2022-12-21)

• 主引用文献: Jiang, X.,Gurel, O.,Mendiaz, E.A.,Stearns, G.W.,Clogston, C.L.,Lu, H.S.,Osslund, T.D.,Syed, R.S.,Langley, K.E.,Hendrickson, W.A.; Structure of the active core of human stem cell factor and analysis of binding to its receptor kit.; EMBO J., 19:3192-3203, 2000; PubMed: 10880433; DOI: 10.1093/emboj/19.13.3192

実験手法

X-RAY DIFFRACTION (2.2 Å)