1S48

Crystal structure of RNA-dependent RNA polymerase construct 1 (residues 71-679) from BVDV

1S48 の概要

• エントリーDOI: 10.2210/pdb1s48/pdb
• 関連するPDBエントリー: 1S49 1S4F
• 分子名称: RNA-dependent RNA polymerase (1 entity in total)
• 機能のキーワード: polymerase, primer independent initiation, de novo initiation, rna virus, bvdv, bovine viral diarrhea virus, replication, rna binding protein
• 由来する生物種: Bovine viral diarrhea virus 1
• 細胞内の位置: E(rns) glycoprotein: Host membrane; Peripheral membrane protein. Envelope glycoprotein E2: Host cell surface. Cysteine protease NS2: Host membrane; Multi- pass membrane protein (Potential): P19711
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 70490.74

構造登録者

Choi, K.H.,Groarke, J.M.,Young, D.C.,Kuhn, R.J.,Smith, J.L.,Pevear, D.C.,Rossmann, M.G. (登録日: 2004-01-15, 公開日: 2004-04-06, 最終更新日: 2011-07-13)

• 主引用文献: Choi, K.H.,Groarke, J.M.,Young, D.C.,Kuhn, R.J.,Smith, J.L.,Pevear, D.C.,Rossmann, M.G.; The structure of the RNA-dependent RNA polymerase from bovine viral diarrhea virus establishes the role of GTP in de novo initiation.; Proc.Natl.Acad.Sci.Usa, 101:4425-4430, 2004; PubMed: 15070734; DOI: 10.1073/pnas.0400660101

実験手法

X-RAY DIFFRACTION (3 Å)