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1S3E

Crystal structure of MAOB in complex with 6-hydroxy-N-propargyl-1(R)-aminoindan

Summary for 1S3E
Entry DOI10.2210/pdb1s3e/pdb
Related1S2Q 1S2Y 1S3B
DescriptorAmine oxidase [flavin-containing] B, FLAVIN-ADENINE DINUCLEOTIDE, (3R)-3-(PROP-2-YNYLAMINO)INDAN-5-OL, ... (4 entities in total)
Functional Keywordshuman monoamine oxidase, inhibitor binding, rasagiline, enantioselectivity, flavin, oxidoreductase
Biological sourceHomo sapiens (human)
Cellular locationMitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side: P27338
Total number of polymer chains2
Total formula weight119621.04
Authors
Binda, C.,Hubalek, F.,Li, M.,Herzig, Y.,Sterling, J.,Edmondson, D.E.,Mattevi, A. (deposition date: 2004-01-13, release date: 2004-03-30, Last modification date: 2011-07-13)
Primary citationBinda, C.,Li, M.,Herzig, Y.,Sterling, J.,Edmondson, D.E.,Mattevi, A.
Crystal Structures of Monoamine Oxidase B in Complex with Four Inhibitors of the N-Propargylaminoindan Class.
J.Med.Chem., 47:1767-1774, 2004
Cited by
PubMed: 15027868
DOI: 10.1021/jm031087c
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.6 Å)
Structure validation

217705

건을2024-03-27부터공개중

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