1S0X
Crystal structure of the human RORalpha ligand binding domain in complex with cholesterol sulfate at 2.2A
Summary for 1S0X
Entry DOI | 10.2210/pdb1s0x/pdb |
Descriptor | Nuclear receptor ROR-alpha, CHOLEST-5-EN-3-YL HYDROGEN SULFATE (3 entities in total) |
Functional Keywords | three-layered alpha helical sandwich, nuclear hormone receptor, orphan receptor, ligand binding domain, hormone-growth factor receptor complex, hormone/growth factor receptor |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P35398 |
Total number of polymer chains | 1 |
Total formula weight | 31981.00 |
Authors | Kallen, J.,Schlaeppi, J.M.,Bitsch, F.,Delhon, I.,Fournier, B. (deposition date: 2004-01-05, release date: 2004-02-10, Last modification date: 2023-09-20) |
Primary citation | Kallen, J.,Schlaeppi, J.M.,Bitsch, F.,Delhon, I.,Fournier, B. Crystal structure of the human RORalpha Ligand binding domain in complex with cholesterol sulfate at 2.2 A J.Biol.Chem., 279:14033-14038, 2004 Cited by PubMed: 14722075DOI: 10.1074/jbc.M400302200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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