1S0X

Crystal structure of the human RORalpha ligand binding domain in complex with cholesterol sulfate at 2.2A

1S0X の概要

• エントリーDOI: 10.2210/pdb1s0x/pdb
• 分子名称: Nuclear receptor ROR-alpha, CHOLEST-5-EN-3-YL HYDROGEN SULFATE (3 entities in total)
• 機能のキーワード: three-layered alpha helical sandwich, nuclear hormone receptor, orphan receptor, ligand binding domain, hormone-growth factor receptor complex, hormone/growth factor receptor
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus: P35398
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 31981.00

構造登録者

Kallen, J.,Schlaeppi, J.M.,Bitsch, F.,Delhon, I.,Fournier, B. (登録日: 2004-01-05, 公開日: 2004-02-10, 最終更新日: 2023-09-20)

• 主引用文献: Kallen, J.,Schlaeppi, J.M.,Bitsch, F.,Delhon, I.,Fournier, B.; Crystal structure of the human RORalpha Ligand binding domain in complex with cholesterol sulfate at 2.2 A; J.Biol.Chem., 279:14033-14038, 2004; PubMed: 14722075; DOI: 10.1074/jbc.M400302200

実験手法

X-RAY DIFFRACTION (2.2 Å)