1RXV

Crystal Structure of A. Fulgidus FEN-1 bound to DNA

Summary for 1RXV

• Entry DOI: 10.2210/pdb1rxv/pdb
• Related: 1RWZ 1RXQ 1RXW 1RXZ
• Descriptor: 5'-d(*T*pA*pG*pC*pA*pT*pC*pG*pG), Flap structure-specific endonuclease (2 entities in total)
• Functional Keywords: helical clamp, helix-3 turn-helix, 3' flap binding site, protein-dna complex, dna repair, dna replication, hydrolase-dna complex, hydrolase/dna
• Biological source: Archaeoglobus fulgidus; More
• Total number of polymer chains: 4
• Total formula weight: 81746.44

Authors

Chapados, B.R.,Hosfield, D.J.,Han, S.,Qiu, J.,Yelent, B.,Shen, B.,Tainer, J.A. (deposition date: 2003-12-18, release date: 2004-01-27, Last modification date: 2024-04-03)

• Primary citation: Chapados, B.R.,Hosfield, D.J.,Han, S.,Qiu, J.,Yelent, B.,Shen, B.,Tainer, J.A.; Structural Basis for FEN-1 Substrate Specificity and PCNA-Mediated Activation in DNA Replication and Repair; Cell(Cambridge,Mass.), 116:39-50, 2004; PubMed: 14718165; DOI: 10.1016/S0092-8674(03)01036-5

Experimental method

X-RAY DIFFRACTION (2.5 Å)