1RTM

TRIMERIC STRUCTURE OF A C-TYPE MANNOSE-BINDING PROTEIN

1RTM の概要

• エントリーDOI: 10.2210/pdb1rtm/pdb
• 分子名称: MANNOSE-BINDING PROTEIN-A, CALCIUM ION, CHLORIDE ION, ... (5 entities in total)
• 機能のキーワード: lectin
• 由来する生物種: Rattus norvegicus (Norway rat)
• 細胞内の位置: Secreted: P19999
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 51284.49

構造登録者

Weis, W.I.,Drickamer, K. (登録日: 1994-11-21, 公開日: 1995-02-07, 最終更新日: 2024-10-30)

主引用文献

Weis, W.I.,Drickamer, K.
Trimeric structure of a C-type mannose-binding protein.
Structure, 2:1227-1240, 1994

PubMed Abstract: Mannose-binding proteins (MBPs) are C-type (Ca(2+)-dependent) animal lectins found in serum. They recognize cell-surface oligosaccharide structures characteristic of pathogenic bacteria and fungi, and trigger the neutralization of these organisms. Like most lectins, MBPs display weak intrinsic affinity for monovalent sugar ligands, but bind avidly to multivalent ligands.

PubMed: 7704532
DOI: 10.1016/S0969-2126(94)00124-3

実験手法

X-RAY DIFFRACTION (1.8 Å)