1RTF

COMPLEX OF BENZAMIDINE WITH THE CATALYTIC DOMAIN OF HUMAN TWO CHAIN TISSUE PLASMINOGEN ACTIVATOR [(TC)-T-PA]

Summary for 1RTF

• Entry DOI: 10.2210/pdb1rtf/pdb
• Descriptor: TWO CHAIN TISSUE PLASMINOGEN ACTIVATOR, PHOSPHATE ION, BENZAMIDINE, ... (5 entities in total)
• Functional Keywords: serine protease, fibrinolytic enzymes
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted, extracellular space: P00750
• Total number of polymer chains: 2
• Total formula weight: 30494.35

Authors

Bode, W.,Lamba, D. (deposition date: 1995-11-10, release date: 1997-01-11, Last modification date: 2011-07-13)

• Primary citation: Lamba, D.,Bauer, M.,Huber, R.,Fischer, S.,Rudolph, R.,Kohnert, U.,Bode, W.; The 2.3 A crystal structure of the catalytic domain of recombinant two-chain human tissue-type plasminogen activator; J.Mol.Biol., 258:117-135, 1996; PubMed: 8613982; DOI: 10.1006/jmbi.1996.0238

Experimental method

X-RAY DIFFRACTION (2.3 Å)