1RS2

DHNA complex with 8-Amino-1,3-dimethyl-3,7-dihydropurine-2,6-dione

1RS2 の概要

関連するPDBエントリー1RR5 1RRI 1RRW 1RRY 1RS4 1RSD 1RSI
分子名称Dihydroneopterin aldolase, 8-AMINO-1,3-DIMETHYL-3,7-DIHYDROPURINE-2,6-DIONE (3 entities in total)
機能のキーワード7, dhna, 8-dihydroneop8-amino-1, 3-dimethyl-3, 7-dihydropurine-2, 6-dioneterin aldolase, lyase
由来する生物種Staphylococcus aureus
ポリマー鎖数1
分子量合計13964.81
構造登録者
主引用文献
Sanders, W.J.,Nienaber, V.L.,Lerner, C.G.,McCall, J.O.,Merrick, S.M.,Swanson, S.J.,Harlan, J.E.,Stoll, V.S.,Stamper, G.F.,Betz, S.F.,Condroski, K.R.,Meadows, R.P.,Severin, J.M.,Walter, K.A.,Magdalinos, P.,Jakob, C.G.,Wagner, R.,Beutel, B.A.
Discovery of Potent Inhibitors of Dihydroneopterin Aldolase Using CrystaLEAD High-Throughput X-ray Crystallographic Screening and Structure-Directed Lead Optimization.
J.Med.Chem., 47:1709-1718, 2004
PubMed: 15027862 (主引用文献が同じPDBエントリー)
DOI: 10.1021/jm030497y
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2.31 Å)
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構造検証レポート

ClashscoreRamachandran outliersSidechain outliers180.8%6.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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