1RQI
Active Conformation of Farnesyl Pyrophosphate Synthase Bound to Isopentyl Pyrophosphate and Dimethylallyl S-Thiolodiphosphate
Summary for 1RQI
Entry DOI | 10.2210/pdb1rqi/pdb |
Related | 1RQJ 1RTR |
Descriptor | Geranyltranstransferase, MAGNESIUM ION, DIMETHYLALLYL S-THIOLODIPHOSPHATE, ... (6 entities in total) |
Functional Keywords | isoprenyl synthase, transferase |
Biological source | Escherichia coli |
Total number of polymer chains | 2 |
Total formula weight | 65877.69 |
Authors | Hosfield, D.J.,Zhang, Y.,Dougan, D.R.,Brooun, A.,Tari, L.W.,Swanson, R.V.,Finn, J. (deposition date: 2003-12-05, release date: 2004-03-02, Last modification date: 2024-02-14) |
Primary citation | Hosfield, D.J.,Zhang, Y.,Dougan, D.R.,Brooun, A.,Tari, L.W.,Swanson, R.V.,Finn, J. Structural basis for bisphosphonate-mediated inhibition of isoprenoid biosynthesis J.Biol.Chem., 279:8526-8529, 2004 Cited by PubMed: 14672944DOI: 10.1074/jbc.C300511200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.42 Å) |
Structure validation
Download full validation report