1RQC

Crystals of peptide deformylase from Plasmodium falciparum with ten subunits per asymmetric unit reveal critical characteristics of the active site for drug design

Summary for 1RQC

Related1RL4 1JYM
Descriptorformylmethionine deformylase, COBALT (II) ION (3 entities in total)
Functional Keywordshydrolase
Biological sourcePlasmodium falciparum (malaria parasite P. falciparum)
Total number of polymer chains10
Total molecular weight221069.82
Authors
Robien, M.A.,Nguyen, K.T.,Kumar, A.,Hirsh, I.,Turley, S.,Pei, D.,Hol, W.G. (deposition date: 2003-12-04, release date: 2004-01-20, Last modification date: 2011-07-13)
Primary citation
Robien, M.A.,Nguyen, K.T.,Kumar, A.,Hirsh, I.,Turley, S.,Pei, D.,Hol, W.G.
An improved crystal form of Plasmodium falciparum peptide deformylase
Protein Sci., 13:1155-1163, 2004
PubMed: 15010544 (PDB entries with the same primary citation)
DOI: 10.1110/ps.03456404
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.8 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.263161.4%24.6%3.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution