1RP9

Crystal structure of barley alpha-amylase isozyme 1 (amy1) inactive mutant d180a in complex with acarbose

1RP9 の概要

• エントリーDOI: 10.2210/pdb1rp9/pdb
• 関連するPDBエントリー: 1AMY 1BG9 1HT6 1P6W 1RP8 1RPK
• 分子名称: Alpha-amylase type 1 isozyme, 4,6-dideoxy-4-{[(1S,5R,6S)-3-formyl-5,6-dihydroxy-4-oxocyclohex-2-en-1-yl]amino}-alpha-D-xylo-hex-5-enopyranose-(1-4)-beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 4,6-dideoxy-4-{[(1S,5R,6S)-3-formyl-5,6-dihydroxy-4-oxocyclohex-2-en-1-yl]amino}-alpha-D-xylo-hex-5-enopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: alpha-amylase, barley, isozyme 1, inactive mutant, beta-alpha-barrel, sugar tongs binding site, acarbose, hydrolase
• 由来する生物種: Hordeum vulgare
• 細胞内の位置: Secreted, extracellular space: P00693
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 46634.95

構造登録者

Robert, X.,Haser, R.,Aghajari, N. (登録日: 2003-12-03, 公開日: 2005-06-07, 最終更新日: 2023-08-23)

• 主引用文献: Robert, X.,Haser, R.,Mori, H.,Svensson, B.,Aghajari, N.; Oligosaccharide Binding to Barley {alpha}-Amylase 1; J.Biol.Chem., 280:32968-32978, 2005; PubMed: 16030022; DOI: 10.1074/jbc.M505515200

実験手法

X-RAY DIFFRACTION (2 Å)