1RJ6

Crystal Structure of the Extracellular Domain of Murine Carbonic Anhydrase XIV in Complex with Acetazolamide

1RJ6 の概要

• エントリーDOI: 10.2210/pdb1rj6/pdb
• 関連するPDBエントリー: 1RJ5
• 分子名称: Carbonic anhydrase XIV, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: beta-sheet, alpha-helix, zinc enzyme, lyase
• 由来する生物種: Mus musculus (house mouse)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 60413.08

構造登録者

Whittington, D.A.,Grubb, J.H.,Waheed, A.,Shah, G.N.,Sly, W.S.,Christianson, D.W. (登録日: 2003-11-18, 公開日: 2004-03-09, 最終更新日: 2020-07-29)

• 主引用文献: Whittington, D.A.,Grubb, J.H.,Waheed, A.,Shah, G.N.,Sly, W.S.,Christianson, D.W.; Expression, assay, and structure of the extracellular domain of murine carbonic anhydrase XIV: implications for selective inhibition of membrane-associated isozymes.; J.Biol.Chem., 279:7223-7228, 2004; PubMed: 14660577; DOI: 10.1074/jbc.M310809200

実験手法

X-RAY DIFFRACTION (2.9 Å)